Indapamide: what it is and why people use it

Indapamide is a thiazide-like diuretic commonly used to lower high blood pressure and reduce fluid buildup (edema). If your doctor suggested indapamide, this page gives a clear, practical overview: how it works, typical doses, common side effects, drug interactions, and simple safety tips so you know what to watch for.

How indapamide works and when it's used

Indapamide helps your kidneys remove extra salt and water. That reduces blood volume and eases pressure on blood vessel walls, which lowers blood pressure. Doctors often prescribe it for essential hypertension and for patients who have swelling from heart or kidney conditions. Because it’s long-acting, many people take it once a day.

Typical starting doses are low—often 1.5 mg or 2.5 mg once daily depending on the product and the country. Your doctor will pick the exact dose based on your blood pressure, age, kidney function, and other medications you take.

Common side effects, interactions, and simple precautions

Most people tolerate indapamide well, but watch for dizziness (especially when standing up), increased urination, muscle cramps, or tiredness. It can change blood salts—especially lowering potassium and sodium—so your provider may check blood tests after you start or change the dose.

Drug interactions matter. Indapamide can raise the risk of side effects with lithium, some heart rhythm medicines, and certain diabetes drugs. NSAIDs (like ibuprofen) may reduce how well it works. Low potassium makes drugs like digoxin riskier. Tell your doctor about every medicine, supplement, or herbal product you use.

If you have severe kidney disease, very low blood pressure, or are pregnant or breastfeeding, indapamide may not be right for you. Always follow your prescriber’s advice and ask before making changes.

Practical tips: take indapamide in the morning to avoid nighttime trips to the bathroom; keep hydrated but don’t overdo fluids if your doctor limits them; report any fainting, fast heartbeat, severe muscle weakness, or signs of dehydration right away. Don’t stop the drug suddenly without talking to your clinician—blood pressure can rebound.

Want to compare options? If you’re exploring other diuretics or alternatives for edema or blood pressure control, check related guides like our Furosemide alternatives and Amiloride articles for practical differences and monitoring tips. If you’re thinking of buying meds online, make sure the pharmacy is legitimate and that a doctor approves your prescription.

Questions about dose, side effects, or interactions are worth a quick call to your healthcare team. Indapamide can be very effective when used correctly, and a few routine checks keep it safe and reliable.